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Can probiotics help relieve UTI?

Posted on22 Jun 2020
There is a close correlation between the loss of the normal genital microbiota, particularly Lactobacillus species, and an increased incidence of UTIs, therefore suggesting that repletion may be beneficial.

A recent review in Canada suggested that the mechanisms whereby certain probiotic lactobacilli improve urogenital health include immune modulation, reduction in pathogen ascension from the rectum, and interference with colonisation and survival of pathogens.

A Lactobacillus plantarum and Lactobacillus rhamnosus were shown in vitro to inhibit the adherence of E. coli to the GI tract wall by inducing the production of mucin (a sticky substance coating the epithelial cells known to inhibit the adhesion of pathogens).

A 2011 in vitro study at Reading University also showed two probiotics strains, Lactobacillus acidophilus and Lactobacillus plantarum, to have good anti-bacterial effects in inhibiting E. coli growth. A randomised, double-blind, placebo-controlled trial (RCT) in 2006 showed an oral Lactobacillus rhamnosus and a Lactobacillus reuteri was able to recover vaginal counts of Lactobacillus species following antibiotics and infection by 96% compared to 53% in controls.

A Finnish study in 2003 involving 139 women with RUTIs and 185 without showed that ingesting fermented milk products containing probiotic bacteria more than three times a week was associated with a decreased risk of RUTIs. A more recent trial in Seattle in 2011 gave 100 young women with RUTIs antimicrobials and then randomised the group to receive either a lactobacilli intravaginal suppository probiotic or a placebo daily for five days, then once weekly for 10 weeks.

RUTI occurred in 15% of women receiving the lactobacilli compared with 27% of the placebo group. High-level vaginal colonisation with the lactobacilli strain throughout follow-up was associated with a significant reduction in RUTIs.

All of these probiotic strains are part of the 19 probiotic strains in Lactocran. The encouraging responses in the above studies lead to the possibility that probiotic supplementation could be beneficial in maintaining urinary tract health. All of these probiotic strains are part of the 19 probiotic strains in Lactocran. This shows probiotics can help relieve UTI, manage urinary tract health and lower the incidence of RUTI.
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